Advancing precision medicine with computational modelling
 

Research Projects

Virtual

Metabolic Human

BugTheDrug

Method & Tool

Development

Parkinson's

Disease

Gut-Brain-Axis​ In Alzheimer's Disease

Host-microbe

Co-metabolism

 

Publications

The VMH

A multitude of factors contribute to complex diseases and can be measured with ‘omics’ methods. Databases facilitate data inter-pretation for underlying mechanisms ... 

The COBRA Toolbox

Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental molecular systems biology  ...

Dietary Supplements

Crohn’s disease (CD) is associated with an ecological imbalance of the intestinal microbiota, consisting of hundreds of species. The underlying complexity ...

 

In silico Models

Bacterial biochemical models

Eukaryotic biochemical models

Multi-scale biochemical models

 

© 2019 by Ines Thiele.